Potentiation of cisplatin-induced injury of rat kidney cortical mitochondria by GSH depletion
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چکیده
منابع مشابه
Cisplatin-induced injury to calcium uptake by mitochondria in glutathione-depleted slices of rat kidney cortex.
Changes in functional activities of mitochondria from kidney cortical slices incubated with cisplatin and the glutathione depletor diethylmaleate were examined. Diethylmaleate, which decreased the glutathione level in the slices, enhanced the cisplatin-induced decreases in glutathione level and calcium uptake in the mitochondria. The movement of cisplatin into mitochondria in the slices was not...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1990
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)55317-3